Last week I made some test pages to see how different combinations of tools would look. I printed out a loosely penciled page twice and inked it 2 different ways, then tried toning and coloring each of those. Results:
1) Inked with a metal nib
2) Metal nib inking + flat graytones
3) Metal nib inking + color
4) Inked with a brush
5) Brush inking + halftones
6) Brush inking + color
I also got positive feedback on the watercolor sketches last week, and suggestions that I watercolor the entire book. I am preeeeeetty sure that is not going to happen, because it would be difficult to correct mistakes without redrawing pages (or at least panels) from scratch. On the other hand, I LOVE watercolor comics and I think I might actually be faster at watercoloring than digital coloring.